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Pediatric Epilepsy Center

Pediatric Epilepsy Care

What is Epilepsy?

Epilepsy is a broad term used for a brain disorder that causes seizures. There are many different types of epilepsy. There are also many different kinds of seizures.Β Learn moreΒ about epilepsy and how to keep children with epilepsy safe.

Seizures are typically classified into two main groups: Generalized Seizures & Focal Seizures

  • Generalized seizuresΒ affect both sides of the brain.
  • Absence seizures, sometimes called petit mal seizures, can cause rapid blinking or a few seconds of staring into space.
  • Tonic-clonic seizures, also called grand mal seizures, can make a person
    • Cry out.
    • Lose consciousness.
    • Fall to the ground.
    • Have muscle jerks or spasms.

The person may feel tired after a tonic-clonic seizure.

  • Focal seizuresΒ are located in just one area of the brain. These seizures are also called partial seizures.
  • Simple focal seizuresΒ affect a small part of the brain. These seizures can cause twitching or a change in sensation, such as a strange taste or smell.
  • Complex focal seizuresΒ can make a person with epilepsy confused or dazed. The person will be unable to respond to questions or direction for up to a few minutes.
  • Secondary generalized seizuresΒ begin in one part of the brain, but then spread to both sides of the brain. In other words, the person first has a focal seizure, followed by a generalized seizure.

Seizures may last as long as a few minutes.

(CDC, 2020)

Signs of Seizures in Children
Seizures in children can look different depending on the type, but some common signs to watch for include sudden staring spells with unresponsiveness, uncontrolled jerking movements, stiffening of the body, or loss of consciousness. Some children may appear confused, dazed, or unresponsive for a short period. Others might suddenly drop to the ground or experience repetitive movements like lip-smacking or blinking. In some cases, seizures can cause sudden changes in breathing or skin color. After a seizure, a child may feel tired, confused, or have difficulty speaking. If you suspect your child is having a seizure, stay calm, keep them safe, and seek medical attention.Β 

Epilepsy Care

Our Pediatric Neurology and Neurosurgery Team has extensive training in treating patients with epilepsy. We review all patient medical history to come up with a thorough plan to ensure your child is receiving the care they need. In addition to seeing our Pediatric Neuroscience Team, this care many consist of having the child undergoing an Electroencephalogram (EEG), Neurocognitive Testing, Autonomic Testing, or having a visit with our Nutritionist and/or Psychologist.Β  If you are concerned your child may be having seizures, not matter the magnitude, please call our office to schedule a consultation.Β 

Evaluations For Seizures

Depending on the clinical situation and the pediatric neurologist assessment, an EEG(electroencephalogram) andΒ  MRI (magnetic resonance imaging) brain study may be needed to help with the diagnostic evaluation.Β  Β  It is helpful to prepare your child for the procedures to help reduce anxiety and ensure the process goes smoothly.

For anΒ EEG (electroencephalogram), explain to your child that the test is a safe, painless test that uses small stickers (electrodes) to check brain wave activity by placing stickers on the patient's scalp.Β  There are no needles involved and the EEG does not send any electrical current into your brain.Β  The night before, wash their hair but avoid conditioner, oils, or styling products. Depending on the type of EEG, your child may need to stay awake later or wake up earlier to be sleep-deprived for the test.Β  During the test, there are two important components of the EEG procedure involve activation tests with hyperventilation and photic stimulation.Β  Hyperventilation is simply breathing forcefully for three minutes.Β  There maybe a pinwheel that is used to help a child focus on breathing.Β  Second portion of the activation testing involvesΒ  Photic stimulation similar to a strobe light flashing. These two activation tests may provide helpful information regarding your child's seizure type.Β  Β Reviewing the upcoming parts of the EEG study is helpful to improve the cooperation and anxiety for a child during the testing .Β  Β Bringing your child's favorite toy, blanket, or book can help them feel more comfortable.

For anΒ MRI (magnetic resonance imaging), let your child know the machine makes loud noises with beeping and pinging noises,Β  but is not painful.Β  Β Earrings and rings that are metal need to be removed due to restriction of the magnetic capabilities of the MRI machine.Β  Your child will need to lie on a small mobile exam table which moves inside a tunnel-like machine.Β  Some radiology facilities are able to allow a child to wearΒ  headphones or watch a movie. The children's hospital radiology department may have child life specialist to help ease the child's anxiety with music therapy or other forms of relaxation that may help prior to the procedure. If sedation is needed, follow the doctor’s instructions about food and drink beforehand.Β  Β There maybe a need for intravenous contrast administration with an intravenous line requiring IV placement.Β  Β  Reassure your child that you will be close by and encourage relaxation techniques like deep breathing or listening to a favorite story before the scan.Β 

Talking to your child in a calm and positive way can help ease their fears and make the experience easier for both of you.

A fun activity can be planned shortly afterwards the procedure, going to the park,Β  or a favorite meal to look forward to can be helpful.

Links:Β 

  1. For EEG with pinwheel for hyperventilation and photic stimulation effect.
    https://youtu.be/LpqrEu7V17M?si=nN8ukPjmNVNRvTf7
  1. Β For MRI and various sounds - Texas Children's MR-I Got This - https://youtu.be/JQv3KLjgD5M



Sudden Spells in Children: When there is a concern for aΒ seizure ?Β 

In childhood, a child may experienceΒ paroxysmal events, which are sudden, unexpected episodes that begin abruptly and last for a short time, involving unusual movements, behaviors, or changes in awareness.Β  Most of these episodes areΒ not epilepsyΒ and are part of normal childhood development or other medical conditions.Β  Β  These events can mimic epileptic seizures, and accurate recognition relies on understanding their age-specific patterns and may require appropriate evaluations to differentiate from epileptic seizures.

Among infants and toddlers, gastroesophageal reflux andΒ Sandifer syndromeΒ present with back arching, neck extension, and torsional movements often associated with feeding.Β Shuddering spells, occurring between 6 months and 2 years, manifest as brief tremor-like movements of the head, shoulders, or arms, typically triggered by excitement or fear.

Toddlers aged 1–4 years frequently displayΒ stereotypic movementsΒ such as hand flapping, body rocking, or head banging; these are repetitive and suppressible with distraction.Β Breath-holding spells, most common between 6 months and 4 years, are triggered by frustration, pain, or emotional distress, leading to apnea, cyanosis or pallor, brief loss of consciousness, and occasionally stiffening or myoclonic jerks. These resemble seizures but are characterized byΒ rapid return to baselineΒ and normal neurologic examination between events.

Self-stimulatory behaviorsΒ in toddlers and preschool-aged children involve rhythmic genital rubbing/posturing during quiet wakefulness, often noted in car seats or strollers with restraints.Β Delayed processing staring spellsΒ are most common in preschool and school-aged children (3–10 years), presenting as brief inattentive episodes without automatisms, often mistaken for absence seizures.

Other significant mimickers includeΒ motor ticsΒ (5–10 years), sudden, brief, repetitive movements that are voluntarily suppressible and can resemble myoclonic seizures. Movement disorders such asΒ dystoniaΒ orΒ paroxysmal kinesigenic dyskinesiaΒ may occur across childhood, generally preserving awareness.

Syncope and reflex anoxic events, particularly in toddlers and school-aged children, may mimic seizures with brief tonic posturing or myoclonic jerks due to cerebral hypoperfusion. Triggers include pain, emotional stress, or orthostatic changes, withΒ rapid recovery and no postictal confusion.

Sleep-related physiological movements, includingΒ benign sleep myoclonusΒ andΒ hypnagogic/hypnopompic twitches, are normal developmental phenomena that stop immediately upon arousal.

Importantly,Β Psychogenic Nonepileptic Seizures (PNES)β€”also termedΒ functional neurologic disorder (conversion disorder)β€”can present with convulsive-appearing episodes, eye closure, asynchronous movements, or prolonged unresponsiveness. PNES is rare in early childhood but increases in prevalence in preadolescents and adolescents. These events can closely resemble epileptic seizures, andΒ clinical evaluation alone is insufficientΒ in many cases;Β video-EEG monitoring is requiredΒ to confirm diagnosis and avoid unnecessary antiseizure therapy. Associated psychological stressors, anxiety, or trauma history may be present, and multidisciplinary management (neurology, psychology/psychiatry) is recommended.

Clinical evaluation of seizure mimickers:

Careful observation helps differentiate non-epileptic events from seizures. Caregiver-obtained videos improve diagnostic accuracy. During episodes, testing responsiveness to verbal/tactile stimuli assists in determining level of awareness. Key features of non-epileptic events include preserved consciousness, identifiable triggers, absence of postictal confusion, and age-congruent patterns.Β Video-EEG remains the diagnostic gold standard, particularly when differentiating epilepsy from PNES or other mimickers.

Β 

Pediatric Epilepsy Syndromes

While seizure mimickers are common, true pediatric epileptic syndromes demonstrate characteristic developmental and electroclinical profiles.Β Infantile spasms (West syndrome)Β present between 3–12 months with sudden flexor or extensor spasms in clusters, often upon awakening. Prevalence is 2–5 per 10,000 live births. Early recognition is critical due to risk of developmental regression or stagnation.

In toddlers and preschool-aged children (1–5 years),Β febrile seizuresΒ are most common, affecting 2–5% of children and typically manifesting as brief generalized tonic-clonic seizures associated with fever.

School-aged children (4–10 years) may developΒ childhood absence epilepsy, characterized by frequent brief staring episodes with impaired awareness and subtle automatisms, representing 10–15% of pediatric epilepsies. At this age,Β benign epilepsy with centrotemporal spikes (Rolandic epilepsy)Β manifests with unilateral facial twitching, hypersalivation, and speech arrest, commonly during sleep, accounting for 10–20% of childhood epilepsies.

Less common but clinically significant syndromes includeΒ Landau-Kleffner syndrome (LKS), typically between 3–8 years, characterized by acquired epileptic aphasia and language regression with abnormal sleep-activated epileptiform activity. Prompt treatment is crucial to prevent long-term language impairment.

Juvenile myoclonic epilepsy (JME)Β appears in late childhood or adolescence (10–16 years) with morning myoclonic jerks and risk of generalized tonic-clonic or absence seizures, representing 5–10% of childhood epilepsy.

Across all pediatric ages,Β generalized tonic-clonic seizuresΒ manifest with abrupt loss of consciousness, tonic stiffening, clonic jerking, and postictal sleepiness.Β Focal seizuresΒ may occur at any age, producing motor, sensory, autonomic, or behavioral symptoms with or without impaired awareness.

Early recognition of age-specific seizure types, developmental trajectory, language and cognitive function, and behavioral red flags supports timely diagnosis and optimized neurocognitive outcomes.



What is Electroencephalogram (EEG)?

An electroencephalogram (EEG) is a safe and completely painless test that helps us understand how the brain is working. Small stickers called electrodes are gently placed on the scalp by one of our experienced EEG Technologists. These electrodes do not send electricity into the brain, they simply record the brain’s natural activity, which is always happening, even during sleep.

The EEG shows this activity as gentle wave patterns on a computer screen. Sometimes, we use a video EEG to record what’s happening during the test so our team can see how changes in brain activity relate to movements or symptoms.

What an EEG Can Show

An EEG records patterns of normal and unusual brain activity. When doctors review it, they look at several key features:

  • Overall brain rhythm: How your brain waves look when you are awake, relaxed, or asleep.
  • Symmetry and response: How similar the brain waves are on both sides of the brain and how they change with things like flashing lights or deep breathing.
  • Abnormal firing (epileptiform discharges): These are unusual bursts of activity that suggest a tendency for seizures. They can appear between seizures or even in people who have never had a seizure.
  • Seizure activity: Any actual seizures that happen during the recording.
  • Brain response to specific events: How your brain activity changes during events or symptoms you may be experiencing.

EEG is an important part of diagnosing and managing epilepsy, alongside detailed medical history and other tests. However, some unusual patterns may occur in other conditions too, such as head injuries, infections or inflammation of the brain, stroke and brain tumors.

Why an EEG Is Helpful

For someone being evaluated for seizures or epilepsy, an EEG can help:

  1. Distinguish epileptic from non-epileptic events.
  2. Classify the type of seizure(s) and epilepsy.
    • By looking at the location, type, and triggers of abnormal or unusual brain activity (during and between seizures), doctors can determine the type of seizure(s) and epilepsy.
    • Accurate classification is essential because different seizure types respond to different medications; some medicines that help one type can make another type worse.
  3. Assess treatment effectiveness.
    • EEG can be used as a supportive tool to see how well treatment is controlling seizures.
    • For some types of epilepsy and certain medications, EEG can also show whether abnormal or unusual brain activity between seizures is improving. It is important to note that not all medications change the EEG, even if seizures are well controlled.

Types of EEG Studies at NJPNI

  • Routine EEG (Duration is one-hour)
    • Done right in our office by an EEG Technologist. After placing the electrodes, the test records brain activity for about an hour. During this time, the technologist may ask your child to look at flashing lights or take deep breaths to see how their brain responds.

  • Overnight EEG (Duration is approximately 16 hours)
    • An Overnight EEG may also be performed in the office. We have two Overnight EEG spaces that have full bathrooms, TVs, beds, a crib if necessary, and a comfortable chair for parents to stay the night. Our EEG Technologist is trained to stay overnight in our facility to monitor the patient. During this time, the EEG Tech will place the electrodes and perform similar stimulations as they do during a one-hour EEG. The electrodes will then remain intact for the duration of the study. At times, due to possible patient movement during sleep, an adjustment to the electrodes may be needed to ensure the best possible brain wave recording. An overnight EEG helps us determine whether a patient has any seizure-like activity while asleep that may not have appeared during their one-hour study.
  • Ambulatory EEG (Duration of 24 hours at home)
    • Ambulatory electroencephalography (aEEG) monitoring is an EEG that is recorded at home.Β  It has the ability to record for up to 72 hours.Β  The aEEG increases the chance of recording an event or abnormal changes in the brain wave patterns. With this study, the patient will come into the office first, to have our EEG Technologist place on the electrodes and review the instructions of how to use the Ambulatory EEG monitoring equipment. After the test, you’ll return the device so we can review the results.

What Happens Next

When the EEG is complete, our Epileptologist carefully reviews and interprets the recording. The results are discussed with you at your next visit, along with any next steps or treatment plans.

At NJPNI, our goal is to make every EEG experience as comfortable, calm, and informative as possible for both children and parents.

What is Neurocognitive Testing?

Β Neurocognitive Testing is an assessment procedure that utilizes scientifically validated, objective, and reliable computerized neuropsychological tests to evaluate the neurocognitive status of patients. The testing covers a range of mental processes from simple motor performance, attention, and memory, to executive functions. Age-standardized scoring of the assessment eliminates variability and rater bias. The assessment can be repeated over time to monitor progression of disease and/or response to treatment. With a epilepsy, this will help our team to evaluate your child’s thinking ability and how different areas and systems of the brain are working.Β 

A pattern of your child's strengths and weaknesses will be used to help diagnose the type of epilepsy and plan treatment.

The evaluation will assess:

  • Attention and concentration
  • Executive function skills, such as problem solving, abstract reasoning and mental flexibility
  • Intellectual functioning
  • Language
  • Learning and memory
  • Mood and personality
  • Motor skills
  • Visual-spatial skills, such as perception

What is Autonomic Testing?

Autonomic testing is a neurologic procedure in which the function of the autonomic nervous system is evaluated. The autonomic nervous system is the part of the nervous system that controls your breathing, your blood pressure, your heart rate, the movement of your gastrointestinal tract, your skin temperature, and numerous other functions. To assist in the treatment plan of epilepsy, Autonomic Testing may be recommended by your Pediatric Neurologist to see what might be contributing to the epileptic episodes. This is a pain-free test as well!Β 

What is VNS Therapy?

Vagus Nerve Stimulation (VNS) Therapy is a proven neuromodulation treatment for children ages 4 and older with drug-resistant epilepsy and partial onset seizures. Used as an add-on therapy alongside medication, VNS delivers gentle electrical stimulation to the vagus nerve to help reduce seizure frequency and severity over time. It has been used in more than 40,000 children worldwide and is the most prescribed neuromodulation device for pediatric drug-resistant epilepsy. Studies show that children treated with VNS Therapy often experience fewer, shorter, and less severe seizures, improved recovery after seizures, and meaningful improvements in quality of life during critical stages of development

Learn More About VNS Therapy

Why would we recommend a Nutritionist for Epilepsy?

A balanced diet from different food groups help the body and brain to function, helping us to stay healthy! Our Pediatric Nutritionist can provide you with suggestions on a healthy diet, such as ketogenic diet or modified Atkins diet, that may help reduce the risk of seizures for some people with epilepsy. We will provide you with easy safe recipes to help stay on a healthy track.Β 

Why would we recommend a Psychologist for Epilepsy?

Pediatric Psychological evaluations are individualized comprehensive assessments that target an individual’s patterns of current functioning to better understand cognitive abilities, socio-emotional functioning, behavior, and/or personality. We may refer you to see our Pediatric Psychologist to assist in finding a psychological intervention to fit the needs of your child. This may include, relaxation therapy, cognitive behavior therapy, and education interventions that have been used in studies to reduce the frequency of seizures and improve the quality the life.

When would we recommend Surgical Evaluation?

Surgical Evaluations

Your child has epilepsy that is resistant to medical therapy, and therefore, may be a candidate for surgical procedures targeted at improving and in some cases, even eliminating, his or her seizures. This is the beginning of a process which can last many months during which we will perform further testing and gather additional information to ensure that surgery will be effective and can be done safely. Our top priority is to rid the patient of seizures without causing permanent neurological problems.

Here are some facts you should know about epilepsy:

FACTS

In about 1/3 patients who suffer with seizures, medicine will not achieve control and the American Academy of Neurology recommends referral to a neurosurgeon to consider surgical options (Weibe 2001, Engel 2012, Dwivedi 2017)
Especially in young children with developing brains, repeated seizure activity and sometimes the medicines used to treat seizures, may impair normal brain development and cognitive functioning (Tai 2016, Vendrame 2009, Freitag 2005).
Many neurologists and pediatricians are not aware of the benefits of surgery, do not properly know how to pick patients who might benefit from surgery, and frequently overestimate the risks (Hakimi 2008). As a result, the Institute of Medicine published a report indicating that we are operating on a small fraction of those patients who could truly benefit and in some cases be cured by surgery (Gumnit 2012, England 2012). Many experts have referred to the underutilization of surgery for patients with epilepsy as a β€œnational disaster.”
*If you decide to proceed down the road of considering surgery, the list provide on the back of this page has several important items to help you navigate this lengthy process:

Surgical Process

In addition to brain MRI studies and video EEG monitoring, several other studies may need to be done to determine if a patient is an appropriate candidate for surgery. Altogether this process may take many months.
  • – PET CT scan: this study is performed in the out-patient setting and helps us see abnormally low levels of metabolism in parts of the brain that can be linked to seizure generation
  • – Ictal SPECT: this study generally requires admission to the hospital and shows increased turn-over in areas of the brain that occur at the time of a seizure
  • – MEG scan: one of only about 15 MEG scanners in the country is at Overlook Hospital in Summit, NJ; like an MRI, patients need to be still so you may be instructed to give your child a Benadryl before the procedure to ensure that he/she sleeps and does not move too much
  • – Functional MRI: this helps tell us what parts of the brain are responsible for speech and movement, critical functions to preserve
  • – 3T and/or stealth MRI: 3T MRI uses a high-power magnet and can better detect subtle abnormalities of cortical development; stealth MRI is thin-cut MRI that allows us to perform neuro-navigation (aka β€œbrain GPS”) during surgery
  • – Wada test: this test helps us understand what outcomes are to be expected after epilepsy surgery in regards to speech, memory, cognitive function, and movement
If after performing all the required studies, your child is NOT determined to be a appropriate candidate for brain surgery, that doesn’t mean we can’t still offer treatment.
  • – Special diets (eg. ketogenic diet) can help patients by decreasing the incidence of seizures
  • – A small implant can be placed in the neck called a vagal nerve stimulator (VNS); while this implant rarely cures a patient of epilepsy, it can often significantly reduce the burden of seizures
  • – Patients with epilepsy often suffer from depression, anxiety, poor memory, and problems with concentration and attention; our multi-disciplinary team is trained to identify and address these related problems that affect quality-of-life
Our team works in a collaborative way with neurologists, neuropsychologists, physiatrists, radiologists, and other experts around the state who treat children with seizures.
  • Our chief epilepsy surgeon, The physicians at NJPNI have connections to other surgeons all around the country to assist in expanding our growing knowledge of epilepsy and the surgical and non-surgical options we can provide patients. Almost all operative patients are discussed in multi-disciplinary conferences to obtain a professional consensus.

Additional Epilepsy Resources:
For more information about epilepsy and seizures, you may find these resources helpful:

Epilepsy Foundation: epilepsy.com
CDC Epilepsy Information: cdc.gov/epilepsy

Download this Epilepsy Information here:

Epilepsy Patient Surgical Information Sheet

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Where Are You in Your Child's Epilepsy Journey?

πŸ‘‰ My child was just diagnosed with epilepsy
Schedule a comprehensive evaluation with our pediatric epilepsy specialists.
We'll create a personalized treatment plan and answer all your questions.

πŸ‘‰ Seizures aren't controlled with medication
Our team can evaluate if epilepsy surgery or alternative treatments
may help. We offer advanced surgical options close to home.

πŸ‘‰ We need a second opinion
Our board-certified epileptologists provide thorough evaluations
and expert guidance on treatment options.

πŸ‘‰ We need advanced EEG testing
We offer routine, overnight, and ambulatory EEG with fast results
review by pediatric epilepsy specialists.

No matter where you are, NJPNI's Pediatric Epilepsy Center is here to help.
Serving New Jersey families at 6 convenient locations

πŸ–₯️ Request an Appointment Online

πŸ“ž Call NJPNI

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NOTICE: This website is for informational purposes only and is not intended as medical advice or as a substitute for a patient/physician relationship.

NJPNI is committed to creating a culturally diverse, inclusive and collaborative community for patients and their families, employees and associates where each person is celebrated and has a sense of equal belonging. See our DEI Statement Page for more information.

NJPNI does not exclude, deny benefits to, or otherwise discriminate against any person on the grounds of race, color, or national origin, or on the basis of disability or age in admission to, participation in, or receipt of the services and benefits of any of its programs and activities or in employment therein. This statement is in accordance with the provisions of Title VI of the Civil Rights Act of 1964, Section 504 of the Rehabilitation Act of 1973, the Age Discrimination Act of 1975, and Regulations of the U.S. Department of Health and Human Services issued pursuant to the Acts, Title 45 Code of Federal Regulations part 80, 84, and 91.

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